Prolong your well-being with physician-supervised hormone replacement therapy designed for women in perimenopause, menopause, and beyond.

Understanding the impact of hormone imbalance

As women approach midlife, declining hormone levels can significantly impact daily life. About 85% of women experience at least one symptom that affects their well-being during this transition. Stress, environmental factors, and the demands of daily life often intensify these changes. Without proper support, symptoms can impact energy, mood, relationships, and long-term health.

Hormone replacement therapy can help restore balance by replenishing the hormones your body no longer produces at the same levels, supporting more consistent energy, emotional stability, and a renewed sense of self.

Warning signs to watch for

When estrogen and progesterone levels decline during perimenopause and menopause, women may experience:

  • Fatigue and low energy
  • Irritability and mood changes
  • Brain fog and difficulty concentrating
  • Sleep disturbances and insomnia
  • Irregular or unpredictable cycles
  • Changes in libido
  • Unexplained weight changes or difficulty maintaining weight

If these symptoms are affecting your quality of life, hormone replacement therapy may help. Our board-certified physicians will evaluate your individual needs and medical history to determine if HRT is right for you.

How it works

Your transformation is guided by data, precision, and board-certified medical expertise—every step of the way.

  • 01

    Start Your Care

    • Begin your clinician directed care journey
    • Book Medical Consultation, $79.
    • Check email for patient portal access.
    • Complete intake process in minutes.
  • 02

    Meet Virtually

    • Meet with a licensed medical provider via secure tele health video
    • Review symptoms, labs, and goals
    • Treatment and dosing are determined only if medically appropriate
    • Additional labs ordered if needed
  • 03

    Personalized Medical Oversight

    • Ongoing clinician-directed medical oversight
    • Prescriptions, when appropriate, filled by FDA-regulated pharmacies and shipped to your door

Start with a Medical Consultation

A licensed medical provider will review your symptoms, labs, and goals to determine the most appropriate treatment.
Medical Expert Video Consultation, 30 Minutes
$79.00
  • Virtual consultation with a board-certified clinician
  • 30 minutes of dedicated patient-provider time
  • Choose your treatment with confidence!
*For hormone therapy, recent labs (within 6 months) are required. Your clinician will review existing labs or help arrange testing if needed.
Only required for hormone therapy

Don’t have recent labs?

Your clinician will review any existing labs and order additional testing only if medically necessary.
  • Comprehensive panels
  • Lab locations close to home
  • Results typically in 5 business days
  • Often eligible for insurance pay

Our women's hormone treatment options

Your clinician will recommend the most appropriate treatment and dosing based on your consultation and lab results.

SUPPORT

You have questions, we have answers.

Find answers to common questions about treatment options and our process. If you don't see your question here, our support team is ready to help.

Contact us

What is hormone replacement therapy?

Hormone replacement therapy (HRT) is a treatment designed to restore or rebalance hormones that naturally decline during perimenopause and menopause. By supplementing estrogen and progesterone (and, in some cases, testosterone for specific symptoms such as low libido), HRT can help reduce symptoms associated with hormonal changes and support overall physical, emotional, and cognitive well-being. Treatment is personalized and guided by a physician based on your symptoms, health history, and goals.

How do I know my symptoms are related to a hormone imbalance?

Hormonal changes during perimenopause and menopause can show up in many ways, including fatigue, irritability, low mood, sleep issues, brain fog, irregular cycles, hot flashes, low libido, and unexpected weight changes. If you've noticed persistent shifts in your energy, mood, or overall well-being—especially if you're in your 40s or older—hormones may be contributing. A physician will review your symptoms and medical history to help determine whether hormone therapy is appropriate for you.

What kinds of symptoms can hormone therapy help with?

Many women find relief from symptoms such as:

  • Mood swings and emotional instability
  • Poor sleep or night sweats
  • Brain fog and difficulty concentrating
  • Fatigue and low energy
  • Irregular or heavy cycles
  • Low libido or vaginal discomfort
  • Changes in body composition

Your clinician will tailor your plan to address the symptoms that matter most to you.

Is hormone replacement therapy safe?

Hormone replacement therapy is considered safe and effective for most women when started at the appropriate time and monitored by qualified clinicians. Research shows HRT is safest when started before age 60 or within 10 years of menopause.

Important considerations:

  • Route matters: Transdermal estrogen (patches, gels) doesn't increase blood clot risk, while oral estrogen carries a small increased risk
  • Individual factors: Your physician will carefully evaluate your personal and family health history, including any history of blood clots, certain cancers, or cardiovascular conditions
  • Risk perspective: While combined HRT slightly increases breast cancer risk with long-term use, this risk is smaller than the risks from obesity, alcohol consumption, or smoking

Our providers will work with you to determine if HRT is appropriate for your individual situation and will provide ongoing monitoring to ensure your treatment remains safe and effective.

How long does it take to notice improvement?

Some women begin to feel better within a few weeks, particularly with improvements in sleep and mood. Others may notice more gradual changes over one to three months as hormone levels stabilize. Hot flashes and night sweats often improve within 4-6 weeks, while benefits such as improved bone density and cognitive clarity take longer to develop. Your physician will help set realistic expectations and adjust your plan as needed.

What are the benefits of hormone replacement therapy?

HRT can help ease a wide range of symptoms, including hot flashes, night sweats, fatigue, mood swings, anxiety, poor sleep, brain fog, irregular cycles, low libido, and vaginal discomfort. Many women also experience improved cognitive clarity, emotional stability, and sexual wellness.

For some women, HRT offers crucial long-term health benefits, including:

  • Supporting bone density and reducing osteoporosis risk
  • Modest improvements in metabolic health
  • Improved overall quality of life and vitality

Your results will depend on your individual symptoms, health profile, and treatment plan.

Do I need lab testing before starting treatment?

Yes, lab testing is required before starting hormone therapy.
If you’ve had recent bloodwork within the last 6 months, you can submit those results at no cost, and they will be reviewed during your consultation.

Why lab testing is required:

  • Rule out other conditions: Hormonal symptoms can overlap with thyroid issues, anemia, vitamin deficiencies, and other treatable causes.
  • Establish a baseline: Knowing your hormone levels allows for personalized treatment and accurate progress tracking.
  • Ensure safety: Labs help identify risk factors or contraindications before starting therapy.
  • Optimize results: Detailed data enables a tailored plan rather than a one-size-fits-all approach.

Will I have to stay on hormone replacement therapy forever?

Not necessarily. Some women use hormone therapy to get through transitional phases like perimenopause or menopause (typically 2-5 years). In contrast, others choose longer-term support based on their symptoms, quality-of-life goals, and health considerations. There's no single right answer—it's a personal decision you'll make with your physician based on how you're feeling and what matters most to you. You can reassess your treatment plan at any time.

How often will I need follow-ups or adjustments?

We typically recommend a follow-up 3–4 months after starting treatment to assess your response and make any needed adjustments. After that, most women check in every 3–6 months to ensure treatment remains safe, effective, and aligned with their symptoms.

Some women require more frequent follow-ups early on, while others do well with less frequent monitoring. Your medical provider will recommend a schedule tailored to your needs.

What happens if I decide to stop treatment later?

You can stop treatment at any time. Your medical provider will help you decide the best approach—whether tapering gradually or stopping right away—and explain what to expect.

Some women notice symptoms return after stopping, but these often lessen over time as the body adjusts. Many women choose to pause, modify, or restart treatment as their needs or life stage changes. The decision is always yours, and your care team is here to support you.

Real People, Real Results

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"I just had my consult with Erica at ProlongMD and she truly knows her stuff. She was thorough, patient, and genuinely caring.We focused on sleep, hormones, and my fat loss goals. After reviewing my bloodwork, Erica identified important insights that had been missed by my previous providers.She recommended starting with targeted peptides and supplements through ProlongMD, with more advanced testing as a next step if needed. I am starting a nighttime peptide protocol and am excited to see my results."
Michelle T
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"My experience with Erica was superb! She quickly understood and assessed my needs. I felt heard. I recommend both ProlongMD and Erica particularly for anyone who is thinking through the inevitable implications of aging."
Sarah H
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"At 49 I thought my low energy was due to my high energy job and just getting older. I had terrible brain fog but thought it was because I was ADHD. I was also looking very fluffy and felt bloated so I upped  my training and focused alot on my nutrition. My weight wouldn’t budge. I decided to get some bloodwork done and found out I had no hormones and my thyroid was shot. I went on HRT and now I feel so much better and the weight started coming off. I knew hormones were important for weight loss but I didn’t realize how much. It’s not just calories in calories out. Now I’m committed to helping other women feel good as they age. "
Christy S
Age 54
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"I was shocked at how much has gone unnoticed by my other medical providers over many years, things  I’ve been complaining about for a long time that were identified in my very first visit with the ProlongMD medical expert. I felt truly heard. Her thoroughness, clarity, and proactive approach left me excited and confident about embarking on my new healthcare plan. I finally feel like I have a provider who sees the whole picture and acts swiftly to optimize my health.   Highly recommend  ProlongMD for anyone seeking knowledgeable, attentive care in women’s health and weight loss."
Michelle G
Age 56
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"After surgical menopause in 2019, my weight climbed to 225 pounds despite working out 3–4 times a week and eating well. My A1C was approaching diabetic levels, and nothing seemed to work.Once I started a personalized medical approach that addressed hormone balance and insulin resistance, everything changed. I’ve lost 80 pounds and over 31 inches, dramatically reduced body fat, gained muscle, and brought my A1C back into a healthy range. My liver health has improved, autoimmune flare-ups are less frequent, and I feel stronger than ever.At 49, I’m in the best shape of my life—better than my 20s. My husband also joined the program for metabolic and hormone support and has seen excellent results."
Tiffany E
Age 49
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"Everything with ProlongMD was easy and efficient from the start. Scheduling was quick, the patient portal was simple to use, and uploading documents and completing forms only took a few minutes.The medical staff at ProlongMD were friendly, professional, and highly knowledgeable. The telehealth visit was far more in-depth than I expected—we covered topics my recent in-person visit didn’t, and the conversation felt unhurried and personal.Not having to drive across town saved me a significant amount of time. Overall, ProlongMD delivered convenient, high-quality care without the hassle. I highly recommend it for anyone who’s busy and looking for an affordable, thorough healthcare option."
Michell B.
Age 42
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“I have been having a great experience with Prolong MD! The doctor, Erica, has been extremely understanding and has taken the time to truly learn my health history and goals. She has been very thorough in reviewing my bloodwork and providing clear, thoughtful guidance on nutritional changes and supplements. The entire process has been simple, personalized, and genuinely helpful for improving my overall health.”
James S
Age 42
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"Reaching out to ProlongMD was one of the best decisions I’ve made this year. After years of dealing with a serious health condition that left me chronically fatigued and mentally foggy, I finally found a path forward.The process was simple and efficient—I was able to upload existing labs and meet virtually with a knowledgeable, attentive provider who created a clear, personalized care plan. Pricing was transparent and competitive. Most importantly, the results have been real. Since starting treatment, my energy and mental clarity have noticeably improved, and for the first time in a long while, I feel like I’m moving in the right direction."
Todd H
Age 57