The hidden impact of low testosterone

Low testosterone affects millions of men worldwide, with studies showing that testosterone levels have been declining across all age groups over the past few decades. This isn't just about aging—environmental factors, stress, poor diet, and sedentary lifestyles all contribute to this growing health crisis.

By age 45, nearly 40% of men experience symptoms of low testosterone. Left untreated, low testosterone can significantly impact quality of life, relationships, and overall health outcomes.

Warning signs to watch for

If you're experiencing any of these symptoms, you may have low testosterone:

  • Decreased energy and persistent fatigue
  • Reduced muscle mass and increased body fat
  • Low libido and sexual function
  • Mood changes, irritability, and depression
  • Difficulty concentrating and brain fog
  • Decreased bone density and strength

How it works

Your transformation is guided by data, precision, and board-certified medical expertise—every step of the way.

  • 01

    Start your Care

    • Begin your clinician directed care journey
    • Book Medical Consultation, $79.
    • Check email for patient portal access.
    • Complete intake process in minutes.
  • 02

    Meet Virtually

    • Meet with a licensed medical provider via secure tele health video
    • Review symptoms, labs, and goals
    • Treatment and dosing are determined only if medically appropriate
    • Additional labs ordered if needed
  • 03

    Personalized Medical Oversight

    • Ongoing clinician-directed medical oversight
    • Prescriptions, when appropriate, filled by FDA-regulated pharmacies and shipped to your door

Start with a Medical Consultation

A licensed medical provider will review your symptoms, labs, and goals to determine the most appropriate treatment.
Medical Expert Video Consultation, 30 Minutes
$79.00
  • Virtual consultation with a board-certified clinician
  • 30 minutes of dedicated patient-provider time
  • Choose your treatment with confidence!
*For hormone therapy, recent labs (within 6 months) are required. Your clinician will review existing labs or help arrange testing if needed.
Book Medical Consultation
Only required for hormone therapy

Don't have recent lab work?

Your clinician will review any existing labs and order additional testing only if medically necessary.
  • Comprehensive panels
  • Lab locations close to home
  • Results typically in 5 business days
  • Often eligible for insurance pay

Our testosterone treatment options.

Your clinician will recommend the most appropriate treatment and dosing based on your consultation and lab results.

SUPPORT

You have questions, we have answers.

Find answers to common questions about testosterone therapy, treatment options, and our process. If you don't see your question here, our support team is ready to help.

Contact us

What is testosterone replacement therapy?

Testosterone replacement therapy (TRT) is a medically supervised treatment that restores testosterone and related hormones to healthy levels. It corrects symptoms caused by hormone decline or imbalance and addresses each patient's unique physiology, health history, and goals.

How do I know my symptoms relate to a hormone imbalance?

You should suspect hormone imbalance when symptoms such as low energy, reduced libido, erectile changes, mood shifts, increased body fat, or decreased strength persist despite lifestyle changes. A comprehensive blood panel provides the most accurate way to confirm whether your hormone levels fall outside the healthy range.

What kinds of symptoms can testosterone replacement therapy help with?

TRT improves low energy, diminished sex drive, erectile difficulties, decreased muscle mass, stubborn weight gain, mood instability, mental fog, reduced stamina, and overall decline in well-being. Many men also report enhanced confidence, motivation, and workout performance.

How long does it take to notice improvement?

Most men begin noticing improvements in energy, libido, and mood within a few days or weeks of starting therapy. Strength, body composition, and cognitive benefits often continue developing over weeks and months with consistent treatment and monitoring.

Is testosterone replacement therapy safe?

Qualified clinicians consider TRT safe when they prescribe it appropriately, monitor it with routine lab testing, and adjust it based on your response. Regular follow-ups help ensure your hormone levels stay in a healthy range and minimize the risk of side effects.

What are the benefits of testosterone replacement therapy?

TRT restores energy, improves sexual function, enhances muscle mass and physical performance, stabilizes mood, sharpens mental clarity, and supports a healthier metabolism. For many men, these changes lead to better daily functioning and improved quality of life.

Do I need lab testing before starting treatment?

Yes. Baseline labs are essential for assessing hormone imbalance and determining the most effective treatment plan. We can use existing labs less than 6 months old. Follow-up labs help us track your progress and guide dosing adjustments.

Will I have to stay on testosterone replacement therapy forever?

Not necessarily. Many men choose to continue long-term therapy because it makes them feel significantly better, but treatment duration varies based on personal preference, symptoms, and health goals. You and your clinician can decide together what makes sense for you.

Real People, Real Results

What our patients are saying

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“ProlongMD has been amazing to work with.  Their medical team has extensive experience in using GLP-1s for anti-inflammatory support as well as other cutting-edge peptides for injury and overall training recovery. I highly recommend ProlongMD to those seeking to reclaim the best version of themselves and obtain maximum gains from their fitness endeavors.”  
Tom R
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"At 57, ProlongMD has helped me restart my path toward optimal health. Despite staying active and eating well, I struggled for years with weight, A1c, and the feeling of slowing down. Diet and exercise alone weren’t enough.The ProlongMD team was responsive, thorough, and focused on the full picture of my health. After starting hormone therapy and peptide treatments—alongside continued training and nutrition—I noticed improved focus within days. A month in, my mental clarity, mood, and joint stiffness have all improved, and even my wife has noticed the difference. I’m feeling better physically and working out more consistently, and I’m excited to continue the process."
Rene T
Age 57
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"Reaching out to ProlongMD was one of the best decisions I’ve made this year. After years of dealing with a serious health condition that left me chronically fatigued and mentally foggy, I finally found a path forward.The process was simple and efficient—I was able to upload existing labs and meet virtually with a knowledgeable, attentive provider who created a clear, personalized care plan. Pricing was transparent and competitive. Most importantly, the results have been real. Since starting treatment, my energy and mental clarity have noticeably improved, and for the first time in a long while, I feel like I’m moving in the right direction."
Todd H
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“I have been having a great experience with Prolong MD! The doctor, Erica, has been extremely understanding and has taken the time to truly learn my health history and goals. She has been very thorough in reviewing my bloodwork and providing clear, thoughtful guidance on nutritional changes and supplements. The entire process has been simple, personalized, and genuinely helpful for improving my overall health.”
James S
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"I was shocked at how much has gone unnoticed by my other medical providers over many years, things  I’ve been complaining about for a long time that were identified in my very first visit with the ProlongMD medical expert. I felt truly heard. Her thoroughness, clarity, and proactive approach left me excited and confident about embarking on my new healthcare plan. I finally feel like I have a provider who sees the whole picture and acts swiftly to optimize my health.   Highly recommend  ProlongMD for anyone seeking knowledgeable, attentive care in women’s health and weight loss."
Michelle G
Age 56
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"After surgical menopause in 2019, my weight climbed to 225 pounds despite working out 3–4 times a week and eating well. My A1C was approaching diabetic levels, and nothing seemed to work.Once I started a personalized medical approach that addressed hormone balance and insulin resistance, everything changed. I’ve lost 80 pounds and over 31 inches, dramatically reduced body fat, gained muscle, and brought my A1C back into a healthy range. My liver health has improved, autoimmune flare-ups are less frequent, and I feel stronger than ever.At 49, I’m in the best shape of my life—better than my 20s. My husband also joined the program for metabolic and hormone support and has seen excellent results."
Tiffany E
Age 49
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"At 49 I thought my low energy was due to my high energy job and just getting older. I had terrible brain fog but thought it was because I was ADHD. I was also looking very fluffy and felt bloated so I upped  my training and focused alot on my nutrition. My weight wouldn’t budge. I decided to get some bloodwork done and found out I had no hormones and my thyroid was shot. I went on HRT and now I feel so much better and the weight started coming off. I knew hormones were important for weight loss but I didn’t realize how much. It’s not just calories in calories out. Now I’m committed to helping other women feel good as they age. "
Christy S
Age 54
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"Everything with ProlongMD was easy and efficient from the start. Scheduling was quick, the patient portal was simple to use, and uploading documents and completing forms only took a few minutes.The medical staff at ProlongMD were friendly, professional, and highly knowledgeable. The telehealth visit was far more in-depth than I expected—we covered topics my recent in-person visit didn’t, and the conversation felt unhurried and personal.Not having to drive across town saved me a significant amount of time. Overall, ProlongMD delivered convenient, high-quality care without the hassle. I highly recommend it for anyone who’s busy and looking for an affordable, thorough healthcare option."
Michell B.
Age 32